The dumping syndrome and the hydrogen ion concentration of the gastric contents.
نویسندگان
چکیده
Forty patients after vagotomy (truncal vagotomy 18, selective vagotomy 22) with a drainage procedure were given 200 ml of 50% dextrose by mouth (dumping provocation test), the symptoms induced being noted, and any fall in plasma volume was assessed by serial measurement of the haematocrit. An insulin gastric secretion test was also performed on each patient.TWENTY OF THE PATIENTS HAD DUMPING SYMPTOMS OF VARYING SEVERITY AFTER ORDINARY MEALS: in all 20 patients these symptoms were reproduced by the dumping provocation test, which also produced similar symptoms in a further three patients. The hydrogen ion concentration of the gastric contents was significantly lower in the basal state and after insulin hypoglycaemia in those patients with dumping symptoms than in those without such symptoms. Furthermore there was a significant inverse correlation between the hydrogen ion concentration of the gastric contents in the basal and stimulated state and the rate of plasma volume fall. The results show that the occurrence of the dumping syndrome after vagotomy with a drainage procedure is related to the hydrogen ion concentration of the gastric contents. The possible significance of this finding is discussed.
منابع مشابه
بهبود تجزیه پذیری زیستی دی کلروفنل به کمک اکسیداسیون پیشرفته با معرف فنتون
Background and Aim: 2,4-Dichlorophenol (DCP) is a compound generated in a variety of industrial processes and also by chlorine disinfection of water polluted with phenolic compounds . Dumping of DCP into the environment and water resources is of great concern because of the compound's intense odor and toxicity. DCP is very soluble and resistant to biodegradability so it cannot be removed throu...
متن کاملEffects of glycopyrrolate and cimetidine on gastric volume and acidity in patients awaiting surgery.
Glycopyrrolate or cimetidine was administered before operation to patients undergoing elective surgery. After the induction of anaesthesia, the stomach contents were retrieved and the volume and pH measured. Neither drug diminished the volume of gastric contents compared with control. Glycopyrrolate produced little diminution in hydrogen ion concentration. Cimetidine caused a marked increase in...
متن کاملAdsorption of Cr(III) and Mg(II) from Hydrogen Peroxide Aqueous Solution by Amberlite IR-120 Synthetic Resin
In concentration of hydrogen peroxide, first, the solution should be quite pure, and then, it concentrate with methods such as vacuum distillation and cooling crystallization, because impurities in the hydrogen peroxide solution in high concentrations are causing decomposition of this substance; that is very dangerous. The purpose of this article is separation of chromium and magne...
متن کاملSome aspects of gastric function in the newborn.
Gastric digestion of protein is dependent on the hydrogen ion concentration of the stomach contents. Human gastric juice will digest casein optimally in the pH ranges 1 * 8 to 2 2 and 3 * 5 to 3 * 6. Between and above these ranges hydrolytic activity rapidly declines and is minimal between pH 2-5 and 3*2 (Taylor, 1959). Pepsin is the main enzyme concerned, but others, i.e. parapepsins, have bee...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Gut
دوره 15 3 شماره
صفحات -
تاریخ انتشار 1974